Dicyclohexylcarbodiimide → HCID 178503163, compound

HRID 710526

Reaction equation

HRID 710526 reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][C:11](O)=O)=[CH:5][CH:4]=1.C1CCC(N=C=NC2CCCCC2)CC1.[N:29]1[C:33]2[CH:34]=[CH:35][C:36]([C:38]([NH:40][NH2:41])=O)=[CH:37][C:32]=2[NH:31][CH:30]=1.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:51])=CC=1>>[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][C:11]2[S:51][C:38]([C:36]3[CH:35]=[CH:34][C:33]4[NH:29][CH:30]=[N:31][C:32]=4[CH:37]=3)=[N:40][N:41]=2)=[CH:5][CH:4]=1

Participants

5

Reactant 4

HCID 10868DicyclohexylcarbodiimideHCID 87949Lawesson's reagentHCID 38010983-[4-(Methylsulfanyl)phenyl]propanoic acidHCID 166371191H-benzimidazole-5-carbohydrazide

Product 1

HCID 178503163HCID 178503163, compound

Procedure

The compound was synthesized starting from 3-(4-methylthiophenyl)propionic acid (197 mg; 1 mmol), DCC (206 mg; 1 mmol), benzimidazol-5-carbohydrazide (176 mg; 1 mmol) and Lawesson's reagent (606 mg; 1.5 mmol) as described in method 2; yield: 0.029 mg (8.2%);

Workup

  1. customThe compound was synthesized

Sources & evidence

ORD record
ord-930049d94c9443b3abc9a831d25f7b65
Source dataset
uspto-grants-2015_11
Patent number
US09181233B2

Linked notes

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