Bromine → HCID 178516705, compound

HRID 711362

Reaction equation

HRID 711362 reaction equation
[Br:1]Br.[N:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]=[CH:5][C:4]=1[OH:13]>CC(O)=O>[Br:1][C:10]1[CH:11]=[C:12]2[C:7]([N:6]=[CH:5][C:4]([OH:13])=[N:3]2)=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 24408BromineHCID 178516710HCID 178516710, compound

Product 1

HCID 178516705HCID 178516705, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Bromine (0.895 mL, 15.5 mmol) was added to the solution of quinoxalin-2-ol (1.5 g, 10.3 mmol) in HOAc (15 mL), the mixture was stirred at r.t. for 6 h, and the precipitate was collected and washed with ethyl ether and dried to afford 7-bromoquinoxalin-2-ol as a solid in 90% yield (2 g).

Workup

  1. customthe precipitate was collected
  2. washwashed with ethyl ether
  3. customdried

Sources & evidence

ORD record
ord-f19a51d543424f9b8ea1bc10a8a907b6
Source dataset
uspto-grants-2015_11
Patent number
US09181264B2

Linked notes

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