(2-Methylcyclopropyl)methanol → 2-((2-Methylcyclopropyl)methoxy)-6-nitrobenzonitrile

Reaction equation

[CH3:1][CH:2]1[CH2:4][CH:3]1[CH2:5][OH:6].[N+:7]([C:10]1[CH:17]=[CH:16][CH:15]=[C:14]([N+]([O-])=O)[C:11]=1[C:12]#[N:13])([O-:9])=[O:8]>>[CH3:1][CH:2]1[CH2:4][CH:3]1[CH2:5][O:6][C:14]1[CH:15]=[CH:16][CH:17]=[C:10]([N+:7]([O-:9])=[O:8])[C:11]=1[C:12]#[N:13]

Participants

Reactant 2

HCID 138655(2-Methylcyclopropyl)methanol

HCID 520718Dinitrobenzonitrile

Product 1

HCID 667465932-((2-Methylcyclopropyl)methoxy)-6-nitrobenzonitrileYield 81%

Procedure

Prepared as in Example 166d from (2-methylcyclopropyl)methanol and 2,6-dinitrobenzonitrile in 81% yield. MS 233 (MH+).

Sources & evidence

ORD record: ord-1b38806056de45aca8a6589709a131bc
Source dataset: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09181276B2

Reaction notes

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