Octanoic hydrazide → 4-Hydroxy-1-isoprenyl-N'-octanoyl-2-oxo-1,2-dihydroquinoline-3-carbohydrazide

HRID 716688

Reaction equation

HRID 716688 reaction equation
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]([CH:12]=[CH:13][C:14](=[CH2:16])[CH3:15])[C:4](=[O:17])[C:3]=1[C:18]([O:20]CC)=O.[C:23]([NH:32][NH2:33])(=[O:31])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]>>[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]([CH:12]=[CH:13][C:14](=[CH2:16])[CH3:15])[C:4](=[O:17])[C:3]=1[C:18]([NH:33][NH:32][C:23](=[O:31])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])=[O:20]

Participants

3

Reactant 2

HCID 80556Octanoic hydrazideHCID 131734150Ethyl 4-hydroxy-1-(isoprenyl)-2-oxo-1,2-dihydroquinoline-3-carboxylate

Product 1

HCID 1317341514-Hydroxy-1-isoprenyl-N'-octanoyl-2-oxo-1,2-dihydroquinoline-3-carbohydrazide

Procedure

Reagents: Comp 29 (0.66 mmols, 0.2 g); octanoyl hydrazine (0.73 mmols, 0.12 g). Yield: 0.125 g (22%), white solid, m.p.=114° C.-115° C.

Sources & evidence

ORD record
ord-c0c929f1a1784d11bcb1c55c5bb2a885
Source dataset
uspto-grants-2015_11
Patent number
US09193688B2

Linked notes

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