Dodecanohydrazide → 1-(cyclopropylmethyl)-N'-dodecanoyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbohydrazide

HRID 716691

Reaction equation

HRID 716691 reaction equation
[CH:1]1([CH2:4][N:5]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[C:8]([OH:15])=[C:7]([C:16](OCC)=[O:17])[C:6]2=[O:21])[CH2:3][CH2:2]1.[C:22]([NH:35][NH2:36])(=[O:34])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]>>[CH:1]1([CH2:4][N:5]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[C:8]([OH:15])=[C:7]([C:16]([NH:36][NH:35][C:22](=[O:34])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[O:17])[C:6]2=[O:21])[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 219621DodecanohydrazideHCID 54738243Ethyl 1-(cyclopropylmethyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylate

Product 1

HCID 715474981-(cyclopropylmethyl)-N'-dodecanoyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbohydrazide

Procedure

Reagents: Comp 31 (0.45 mmols, 0.13 g); dodecanoyl hydrazine (0.68 mmols, 0.15 g). Yield: 0.09 g (49%), white solid, m.p.=121° C.-122° C.

Sources & evidence

ORD record
ord-c2787a9dcaa0446ebc12853d80e8e21d
Source dataset
uspto-grants-2015_11
Patent number
US09193688B2

Linked notes

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