1-methyl-1H,4H,5H,6H,7H-pyrazolo(4,3-d)pyrimidine-5,7-dione → 1,3-Dimethyl-1H-pyrazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione

HRID 72186

Reaction equation

HRID 72186 reaction equation
[CH3:1][N:2]1[C:10]2[C:9](=[O:11])[NH:8][C:7](=[O:12])[NH:6][C:5]=2[CH:4]=[N:3]1.N[C:14]1C(C)=NN(C)C=1C(N)=O>>[CH3:1][N:2]1[C:10]2[C:9](=[O:11])[NH:8][C:7](=[O:12])[NH:6][C:5]=2[C:4]([CH3:14])=[N:3]1

Participants

3

Reactant 2

HCID 99422421-methyl-1H,4H,5H,6H,7H-pyrazolo(4,3-d)pyrimidine-5,7-dioneHCID 138229254-amino-1,3-dimethyl-1H-pyrazole-5-carboxamide

Product 1

HCID 138229291,3-Dimethyl-1H-pyrazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione

Procedure

This compound was prepared in an analogous fashion to 1-methyl-1H-pyrazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione, using 4-amino-1,3-dimethyl-1H-pyrazole-5-carb oxamide as the starting material. 1H NMR ((DMSO-d6, 400 MHz) δ ppm 11.02 (s, 2H), 3.97 (s, 3H), 2.20 (s, 3H).

Sources & evidence

ORD record
ord-0ec308e2321f42a19399292574e2e552
Source dataset
uspto-grants-2014_09
Patent number
US08828990B2

Linked notes

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