2-Chloro-4,5-difluorobenzoyl Isocyanate → HCID 21883897, compound
Reaction equation
[Cl:1][C:2]1[CH:12]=[C:11]([F:13])[C:10]([F:14])=[CH:9][C:3]=1[C:4]([N:6]=[C:7]=[O:8])=[O:5].[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([C:22]2[N:23]=[N:24][C:25]([CH3:29])=[C:26]([CH3:28])[N:27]=2)=[CH:18][C:17]=1[NH2:30]>C(#N)C>[Cl:1][C:2]1[CH:12]=[C:11]([F:13])[C:10]([F:14])=[CH:9][C:3]=1[C:4]([NH:6][C:7]([NH:30][C:17]1[CH:18]=[C:19]([C:22]2[N:23]=[N:24][C:25]([CH3:29])=[C:26]([CH3:28])[N:27]=2)[CH:20]=[CH:21][C:16]=1[Cl:15])=[O:8])=[O:5]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The solution of equivalent amounts of 2-chloro-4,5-difluorobenzoyl isocyanate was added dropwise to the solution of 75 mg of 2-chloro-5-(5,6-dimethyl-[1,2,4]triazin-3-yl)phenylamine in 8 ml of acetonitrile and the mixture was stirred at room temperature for 30 minutes. The solid was filtered off with suction and dried under reduced pressure.