3-Furanmethanol → HCID 21884567, compound

Reaction equation

F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][C:3]=1[C:11]1[O:12][C:13]2[CH:19]=[CH:18][C:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[CH:16][C:14]=2[N:15]=1.[O:26]1[CH:30]=[CH:29][C:28]([CH2:31][OH:32])=[CH:27]1>>[N+:8]([C:5]1[CH:6]=[CH:7][C:2]([O:32][CH2:31][C:28]2[CH:29]=[CH:30][O:26][CH:27]=2)=[C:3]([C:11]2[O:12][C:13]3[CH:19]=[CH:18][C:17]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)=[CH:16][C:14]=3[N:15]=2)[CH:4]=1)([O-:10])=[O:9]

Participants

Reactant 2

HCID 204493-Furanmethanol

HCID 218843342-(2-Fluoro-5-nitrophenyl)-5-phenylbenzoxazole

Product 1

HCID 21884567HCID 21884567, compound

Procedure

Prepared by the method of Example 44a), from 2-(2-fluoro-5-nitrophenyl)-5-phenylbenzoxazole (400 mg, 1.2 mmol) in 3-furanmethanol (2 ml) the subtitle compound was obtained (392 mg, 79%). The product was used directly in the next step without purification.

Sources & evidence

ORD record: ord-29debf60f1a54851bf71564ba13ce5e5
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07138425B2

Reaction notes

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