3-(1-Acetylpiperidin-4-yl)propanoic acid → 9-[3-(1-Acetyl-4-piperidinyl)propanoyl]-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one

Participants

Role	Name	HCID	Charge
Reactant	3-(1-Acetylpiperidin-4-yl)propanoic acid	HCID 9855751	—
Reactant	1,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinolin-3-one	HCID 13694564	—
Product	9-[3-(1-Acetyl-4-piperidinyl)propanoyl]-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one	HCID 21887765	—

Reaction Steps

Using 3-(1-acetyl-4-piperidinyl)propanoic acid (13.8 g) and 2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one (10.8 g) according to the same method as that of Reference Example 172, the title compound was obtained as colorless crystals (15.5 g) having a melting point of 130 to 131° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07138533B2
Source dataset	uspto-grants-2006_11
ORD ID	ord-1c0ecefbfb5f423e8515f598f7c9b792
Source note	uspto-grants-2006_11