2,1,3-Benzothiadiazol-5-ylmethanol → 2,1,3-Benzothiadiazole-5-carbaldehyde

HRID 723518

Reaction equation

HRID 723518 reaction equation

[N:1]1[S:5][N:4]=[C:3]2[CH:6]=[C:7]([CH2:10][OH:11])[CH:8]=[CH:9][C:2]=12>ClCCl.[O-2].[O-2].[Mn+4]>[N:1]1[S:5][N:4]=[C:3]2[CH:6]=[C:7]([CH:10]=[O:11])[CH:8]=[CH:9][C:2]=12

Participants

4

Reactant 1

HCID 27762942,1,3-Benzothiadiazol-5-ylmethanol

Product 1

HCID 27762902,1,3-Benzothiadiazole-5-carbaldehyde

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalyst

HCID 6344DichloromethaneSolvent

Procedure

This was prepared by oxidation of benzo[1,2,5]thiadiazol-5-yl-methanol (2a) with manganese dioxide in dichloromethane by the method of Example (4c).

Sources & evidence

ORD record: ord-c24eaf83cafd42cebb258a0d8ec55660
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07141564B2

Linked notes

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