Maleic Anhydride → 1-(4-bromo-3-methylphenyl)-1H-pyrrole-2,5-dione
Reaction equation
[Br:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[CH3:9].[C:10]1(=O)[O:15][C:13](=[O:14])[CH:12]=[CH:11]1>>[Br:1][C:2]1[CH:8]=[CH:7][C:5]([N:6]2[C:13](=[O:14])[CH:12]=[CH:11][C:10]2=[O:15])=[CH:4][C:3]=1[CH3:9]Participants
3
Procedure
4-Bromo-3-methylaniline (1.55 g, 8.33 mmol) and maleic anhydride (0.898 g,
Sources & evidence
- ORD record
- ord-6b09086f1abe4f7cafc196fcbc9e73b9
- Source dataset
- uspto-grants-2006_11
- Patent number
- US07141578B2
Reaction notes
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