2,2-Difluoroacetyl chloride → HCID 178447842, compound

HRID 727759Notes

Reaction equation

HRID 727759 reaction equation
[CH2:1]([C@H:4]1[CH2:9][CH2:8][C@H:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:12][CH:11]=2)[CH2:6][CH2:5]1)[CH2:2][CH3:3].[F:22][CH:23]([F:27])[C:24](Cl)=[O:25]>>[F:22][CH:23]([F:27])[C:24]([C:19]1[CH:20]=[CH:21][C:16]([C:13]2[CH:14]=[CH:15][C:10]([C@H:7]3[CH2:6][CH2:5][C@H:4]([CH2:1][CH2:2][CH3:3])[CH2:9][CH2:8]3)=[CH:11][CH:12]=2)=[CH:17][CH:18]=1)=[O:25]

Participants

3

Reactant 2

HCID 27368902,2-Difluoroacetyl chlorideHCID 178447833HCID 178447833, compound

Product 1

HCID 178447842HCID 178447842, compound

Procedure

The preparation is carried out analogously to Example 4 from 0.5 mol of 4-(trans-4-propylcyclohexyl)biphenyl and 0.5 mol of difluoroacetyl chloride.

Sources & evidence

ORD record
ord-e09817599e91451d92c5b1d8fe770a70
Source dataset
uspto-grants-1991_09
Patent number
US05045229

Reaction notes

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