4-[1-(1-Imidazolyl)-butyl]-benzophenone → alpha-[4-[1-(1-Imidazolyl)-butyl]-phenyl]-benzyl alcohol
Reaction equation
[N:1]1([CH:6]([C:10]2[CH:23]=[CH:22][C:13]([C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[O:15])=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1.B.[Na]>O1CCOCC1.O>[N:1]1([CH:6]([C:10]2[CH:23]=[CH:22][C:13]([CH:14]([OH:15])[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:12][CH:11]=2)[CH2:7][CH2:8][CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
By reduction of the ketone of example 17 with sodium boron hydride in dioxane/water (90:10); boiling point 250° C./0.03 mbar.
Sources & evidence
- ORD record
- ord-1a0338175b774e6cb626f2aaf3732d1f
- Source dataset
- uspto-grants-1991_09
- Patent number
- US05045558
Reaction notes
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