2-Aminomethyl-2-octadecylcarbamoyloxymethyltetrahydrofuran → 2-(3-Chloropropylsulfonylaminomethyl)-2-octadecylcarbamoyloxymethyltetrahydrofuran
Reaction equation
[NH2:1][CH2:2][C:3]1([CH2:8][O:9][C:10](=[O:30])[NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH2:7][CH2:6][CH2:5][O:4]1.[Cl:31][CH2:32][CH2:33][CH2:34][S:35](NCC(OC)CSCCCCCCCCCCCCCCCC)(=[O:37])=[O:36]>>[Cl:31][CH2:32][CH2:33][CH2:34][S:35]([NH:1][CH2:2][C:3]1([CH2:8][O:9][C:10](=[O:30])[NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH2:7][CH2:6][CH2:5][O:4]1)(=[O:37])=[O:36]Participants
3
Procedure
2-Aminomethyl-2-octadecylcarbamoyloxymethyltetrahydrofuran IVb2 is allowed to react and worked by the same procedure as described in (4). The summary of the experimental condition and the physical data of the prodcut are listed in the Table 7.
Workup
- customto react