HCID 86760946, compound → 2-Amino-1-(4-fluorophenyl)-2-(2-isopropoxypyridin-4-yl)ethanone hydrochloride

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:22])[C:9]([C:12]2[CH:17]=[CH:16][N:15]=[C:14]([O:18][CH:19]([CH3:21])[CH3:20])[CH:13]=2)=[N:10]O)=[CH:4][CH:3]=1.Cl.NC(C1C=CN=C([Cl:41])C=1)C(C1C=CC(F)=CC=1)=O>>[ClH:41].[NH2:10][CH:9]([C:12]1[CH:17]=[CH:16][N:15]=[C:14]([O:18][CH:19]([CH3:21])[CH3:20])[CH:13]=1)[C:8]([C:5]1[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=1)=[O:22]

Participants

Reactant 2

HCID 86760946HCID 86760946, compound

HCID 136335781HCID 136335781, compound

Product 1

HCID 690546492-Amino-1-(4-fluorophenyl)-2-(2-isopropoxypyridin-4-yl)ethanone hydrochloride

Procedure

23c was prepared from 22c (2.0 g; 7.6 mmol) using the method described in the synthesis of 23a.

Sources & evidence

ORD record: ord-2a74ffc9165443c9b44c31843a76e738
Source dataset: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07582660B2

Reaction notes

Loading…