Methyl 4-(Chlorosulfonyl)benzoate → Methyl 4-(N-(benzofuran-6-ylmethyl)sulfamoyl)benzoate

HRID 73059

Reaction equation

HRID 73059 reaction equation
Cl[S:2]([C:5]1[CH:14]=[CH:13][C:8]([C:9]([O:11][CH3:12])=[O:10])=[CH:7][CH:6]=1)(=[O:4])=[O:3].[O:15]1[C:19]2[CH:20]=[C:21]([CH2:24][NH2:25])[CH:22]=[CH:23][C:18]=2[CH:17]=[CH:16]1>>[O:15]1[C:19]2[CH:20]=[C:21]([CH2:24][NH:25][S:2]([C:5]3[CH:14]=[CH:13][C:8]([C:9]([O:11][CH3:12])=[O:10])=[CH:7][CH:6]=3)(=[O:4])=[O:3])[CH:22]=[CH:23][C:18]=2[CH:17]=[CH:16]1

Participants

3

Reactant 2

HCID 4738388Methyl 4-(Chlorosulfonyl)benzoateHCID 47002760Benzofuran-6-ylmethanamine

Product 1

HCID 66837871Methyl 4-(N-(benzofuran-6-ylmethyl)sulfamoyl)benzoate

Procedure

The titled compound was prepared according to the procedure described in step-1 of Example 1 from methyl 4-(chlorosulfonyl)benzoate and benzofuran-6-ylmethanamine.

Sources & evidence

ORD record
ord-34a541df39a44606a9b2044b4e2afc25
Source dataset
uspto-grants-2014_09
Patent number
US08829026B2

Linked notes

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