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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 73067Generated: October 25, 2026

2,3-Dichloro-5-(trifluoromethyl)pyridine → Methyl 4-(N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((1-methyl-1H-indol-5-yl)methyl)sulfamoyl)benzoate

https://huagongshe.com/reaction/73067

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dichloro-5-(trifluoromethyl)pyridineHCID 112234—
ReactantMethyl 4-(N-((1-methyl-1H-indol-5-yl)methyl)sulfamoyl)benzoateHCID 66837934—
ProductMethyl 4-(N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((1-methyl-1H-indol-5-yl)methyl)sulfamoyl)benzoateHCID 66837876—

Reaction Steps

The titled compound was prepared according to the procedure described in step-2 of Example 1 from 2,3-dichloro-5-(trifluoromethyl)pyridine and methyl 4-(N-((1-methyl-1H-indol-5-yl)methyl)sulfamoyl)benzoate (step-1 of Example 6).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08829026B2
Source datasetuspto-grants-2014_09
ORD IDord-8e3d8c7118ea4b54b84116192beea261
Source noteuspto-grants-2014_09