2,3-Dichloro-5-(trifluoromethyl)pyridine → HCID 66837888, compound

HRID 73081

Reaction equation

HRID 73081 reaction equation
Cl[C:2]1[C:7]([Cl:8])=[CH:6][C:5]([C:9]([F:12])([F:11])[F:10])=[CH:4][N:3]=1.[CH2:13]([N:15]1[CH:23]=[C:22]2[C:17]([CH:18]=[CH:19][C:20]([CH2:24][NH:25][S:26]([C:29]3[CH:38]=[CH:37][C:32]([C:33]([O:35][CH3:36])=[O:34])=[CH:31][CH:30]=3)(=[O:28])=[O:27])=[CH:21]2)=[N:16]1)[CH3:14]>>[Cl:8][C:7]1[C:2]([N:25]([CH2:24][C:20]2[CH:19]=[CH:18][C:17]3[C:22](=[CH:23][N:15]([CH2:13][CH3:14])[N:16]=3)[CH:21]=2)[S:26]([C:29]2[CH:30]=[CH:31][C:32]([C:33]([O:35][CH3:36])=[O:34])=[CH:37][CH:38]=2)(=[O:28])=[O:27])=[N:3][CH:4]=[C:5]([C:9]([F:12])([F:11])[F:10])[CH:6]=1

Participants

3

Reactant 2

HCID 1122342,3-Dichloro-5-(trifluoromethyl)pyridineHCID 66837834Methyl 4-(N-((2-ethyl-2H-indazol-5-yl)methyl)sulfamoyl)benzoate

Product 1

HCID 66837888HCID 66837888, compound

Procedure

The titled compound was prepared according to the procedure described in step-2 of Example 1 from 2,3-dichloro-5-(trifluoromethyl)pyridine and methyl 4-(N-((2-ethyl-2H-indazol-5-yl)methyl)sulfamoyl)benzoate (step-5 of Example 13).

Sources & evidence

ORD record
ord-1a80b42781bd45dcb1885371b885eb67
Source dataset
uspto-grants-2014_09
Patent number
US08829026B2

Linked notes

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