2,3-Dichloro-5-(trifluoromethyl)pyridine → HCID 66837851, compound

HRID 73104

Reaction equation

HRID 73104 reaction equation
Cl[C:2]1[C:7]([Cl:8])=[CH:6][C:5]([C:9]([F:12])([F:11])[F:10])=[CH:4][N:3]=1.[CH3:13][C:14]1[CH:15]=[C:16]([CH:21]=[CH:22][C:23]=1[S:24](=[O:38])(=[O:37])[NH:25][CH2:26][C:27]1[CH:28]=[C:29]2[C:33](=[CH:34][CH:35]=1)[N:32]([CH3:36])[N:31]=[CH:30]2)[C:17]([O:19][CH3:20])=[O:18]>>[Cl:8][C:7]1[C:2]([N:25]([CH2:26][C:27]2[CH:28]=[C:29]3[C:33](=[CH:34][CH:35]=2)[N:32]([CH3:36])[N:31]=[CH:30]3)[S:24]([C:23]2[CH:22]=[CH:21][C:16]([C:17]([O:19][CH3:20])=[O:18])=[CH:15][C:14]=2[CH3:13])(=[O:38])=[O:37])=[N:3][CH:4]=[C:5]([C:9]([F:12])([F:11])[F:10])[CH:6]=1

Participants

3

Reactant 2

HCID 1122342,3-Dichloro-5-(trifluoromethyl)pyridineHCID 66837895methyl 3-methyl-4-(N-((1-methyl-1H-indazol-5-yl)methyl)sulfamoyl)benzoate

Product 1

HCID 66837851HCID 66837851, compound

Procedure

The titled compound was prepared according to the procedure described in step-2 of Example 1 from 2,3-dichloro-5-(trifluoromethyl)pyridine and methyl 3-methyl-4-(N-((1-methyl-1H-indazol-5-yl)methyl)sulfamoyl)benzoate (step-2 of Example 26).

Sources & evidence

ORD record
ord-ed24c4738c804372be49ea828bbcca85
Source dataset
uspto-grants-2014_09
Patent number
US08829026B2

Linked notes

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