Cyclohexanecarboxamide → Cyclohexanecarbothioamide

HRID 73598

Reaction equation

[CH:1]1([C:7]([NH2:9])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:19])=CC=1>>[CH:1]1([C:7](=[S:19])[NH2:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

Reactant 2

HCID 14283Cyclohexanecarboxamide

HCID 87949Lawesson's reagent

Product 1

HCID 12336049Cyclohexanecarbothioamide

Procedure

Following Method 3, cyclohexanecarboxamide and Lawesson's reagent were reacted, yielding cyclohexanecarbothioamide. LCMS (m/z): 144.1 (MH+); LC Rt=5.10 min.

Workup

customwere reacted

Sources & evidence

ORD record: ord-e89532cfc9aa4bf1a9d4183dc46c277c
Source dataset: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08829193B2

Linked notes

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