Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 736309Generated: October 27, 2026

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one → (3-Nitro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-amine

https://huagongshe.com/reaction/736309

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-oneHCID 567033—
Reactant3-Nitrophenylguanidine NitrateHCID 178512513—
Product(3-Nitro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-amineHCID 986087269.7%

Reaction Steps

3-Nitrophenyl-guanidine nitrate (28 g, 0.12 mol) and 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one (16.9 g, 0.09 mol) were reacted according to the same procedure as Step 1.3 of Preparation 1 to give N-(3-nitrophenyl)-4-(3-pyridyl)-2-pyrimidine-amine (18.4 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07595323B2
Source datasetuspto-grants-2009_09
ORD IDord-18ee62cb361345d79978b33f89b667b2
Source noteuspto-grants-2009_09