Idazoxan Hydrochloride → Idazoxan

Reaction equation

[CH:1]1[CH:2]=[CH:3][C:4]2[O:10][CH:9]([C:11]3[NH:15][CH2:14][CH2:13][N:12]=3)[CH2:8][O:7][C:5]=2[CH:6]=1.Cl.Cl.N1(C2OC3C=CC=CC=3OC2)CCN=C1>>[CH:1]1[CH:2]=[CH:3][C:4]2[O:10][CH:9]([C:11]3[NH:15][CH2:14][CH2:13][N:12]=3)[CH2:8][O:7][C:5]=2[CH:6]=1

Participants

Reactant 2

HCID 154494Idazoxan Hydrochloride

HCID 66775656HCID 66775656, compound

Product 1

HCID 54459Idazoxan

Procedure

Idazoxan hydrochloride belongs to the category of α2-adrenoreceptor antagonists. The chemical name of this molecule is 2-(2-imidazolinyl)-1,4-benzodioxane hydrochloride and its molecular formula is C11H12N2O2HCl. Idazoxan is provided in the form of a slightly hygroscopic, white to substantially white powder which is readily soluble in water and methanol and which is soluble to fairly soluble in ethanol.

Sources & evidence

ORD record: ord-9081c8a816d442fc86072676bb83cb4c
Source dataset: uspto-grants-2009_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07595335B2

Reaction notes

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