Ammonia → 1H-Isoindole-1,3(2H)-dione, hexahydro-

HRID 745205

Reaction equation

[CH:1]12[C:10](=[O:11])O[C:7](=[O:8])[CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6]2.[NH3:12]>>[CH:1]12[C:10](=[O:11])[NH:12][C:7](=[O:8])[CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6]2

Participants

Reactant 2

HCID 222Ammonia

HCID 85689Hexahydrophthalic anhydride

Product 1

HCID 735591H-Isoindole-1,3(2H)-dione, hexahydro-

Procedure

A mixture of 1,2-cyclohexanedicarboxylic anhydride (3 g; 19.5 mmol) and 29% aqueous ammonia (3.4 g) was heated and kept at an inner temperature of 180°-190° C. for 2 hours to give cyclohexane-1,2-dicarboximide. M.P. 132°-136° C.

Workup

temperaturewas heated

Sources & evidence

ORD record: ord-2eaf246c17244b308780dd9329257100
Source dataset: uspto-grants-1986_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04598078

Linked notes

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