HCID 53694269, compound → HCID 13655191, compound
Reaction equation
[C:1]1(=[O:28])[N:5]([CH2:6][C:7]2[CH:12]=[CH:11][C:10]([CH:13]=[CH:14][C:15]3[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][CH:16]=3)=[CH:9][CH:8]=2)[C:4](=[O:23])[C:3]2=[CH:24][CH:25]=[CH:26][CH:27]=[C:2]12>C(Cl)(Cl)Cl.[C].[Pd]>[C:4]1(=[O:23])[N:5]([CH2:6][C:7]2[CH:8]=[CH:9][C:10]([CH2:13][CH2:14][C:15]3[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][CH:16]=3)=[CH:11][CH:12]=2)[C:1](=[O:28])[C:2]2=[CH:27][CH:26]=[CH:25][CH:24]=[C:3]12Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
Catalytic reduction of a solution of 9 g of 4-[2-(4-phthalimidomethylphenyl)ethenyl]benzonitrile in 300 ml of chloroform was carried out with 2 g of a 5% palladium-carbon as catalyst. The reaction mixture was filtered from the spent catalyst and the filtrate was concentrated under reduced pressure. Ether was added to the residue and the precipitated crystals were collected by filtration to obtain 8.5 g of 4-[2-(4-phthalimidomethylphenyl)ethyl]benzonitrile; m.p. 194°-197° C.