Bromine → 1-(Benzenesulfonyl)-3-bromopropan-2-one
Reaction equation
[C:1]1([S:7]([CH2:10][C:11](=[O:13])[CH3:12])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:14]Br>C(Cl)(Cl)(Cl)Cl>[Br:14][CH2:12][C:11](=[O:13])[CH2:10][S:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)(=[O:8])=[O:9]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a stirred suspension of 100.0 g (0.504 mole) phenylsulfonylacetone in 500 ml carbon tetrachloride, 80 g [25.7 ml (0.5 mole)] bromine dissolved in 75 g carbon tetrachloride were added dropwise. The reaction mixture was stirred at ambient temperature overnight. The reaction mixture was filtered, and the precipitate was washed with hexane to give 139.8 g of the above-identified product.
Workup
- additionwere added dropwise
- filtrationThe reaction mixture was filtered
- washthe precipitate was washed with hexane
Sources & evidence
- ORD record
- ord-c308884e5aba4fbd8ca1de442eb9fee8
- Source dataset
- uspto-grants-1986_07
- Patent number
- US04602030
Reaction notes
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