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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 74665Generated: October 26, 2026

Bms-973013 → HCID 58386605, compound

https://huagongshe.com/reaction/74665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBms-973013HCID 22293182—
Reactant(2-Chloro-pyridin-4-yl)-(5,6-difluoro-2,3-dihydro-indol-1-yl)-methanoneHCID 58386704—
SolventN-methyl-2-pyrrolidoneHCID 13387—
ProductHCID 58386605HCID 58386605—

Reaction Steps

1.0 g (4.6 mmol) 1-piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one, 0.45 g (1.5 mmol) (2-chloro-pyridin-4-yl)-(5,6-difluoro-2,3-dihydro-indol-1-yl)-methanone were stirred in 4 mL of NMP for 4 h at 130° C. The reaction mixture was purified by HPLC. The product-containing fractions were combined and freeze-dried.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08829006B2
Source datasetuspto-grants-2014_09
ORD IDord-032d9bc1f83c41c89fa34d6aa31f8612
Source noteuspto-grants-2014_09