n,n-Bis(2-cyanoethyl)hexylamine → n,n-Bis(3-aminopropyl)hexylamine
Reaction equation
[C:1]([CH2:3][CH2:4][N:5]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH2:6][CH2:7][C:8]#[N:9])#[N:2].[H][H]>O1CCOCC1>[NH2:2][CH2:1][CH2:3][CH2:4][N:5]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH2:6][CH2:7][CH2:8][NH2:9]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
31.0 g of N,N-bis(2-cyanoethyl)hexylamine, 4.65 g of RaneyCo, 150 ml of 1,4-dioxane was charged to an autoclave, and hydrogen addition reaction was carried out by supplying hydrogen at an initial pressure of 9.1 MPa at 110° C. for 2 hours. After removing a catalyst by filtration, the obtained filtrate was concentrated and dried to obtain 32.4 g of a target compound as a pale red oily product.
Workup
- customat 110° C.
- customfor 2 hours
- customAfter removing a catalyst
- filtrationby filtration
- concentrationthe obtained filtrate was concentrated
- customdried
Sources & evidence
- ORD record
- ord-7e8ee36758c7485db6b2a8f14bebde0b
- Source dataset
- uspto-grants-2014_09
- Patent number
- US08830811B2
Reaction notes
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