5-Bromo-2-oxindole → 5-Thien-2-yl-1,3-dihydro-2H-indol-2-one
Reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2.C([Sn](CCCC)(CCCC)[C:17]1[S:18][CH:19]=[CH:20][CH:21]=1)CCC>>[S:18]1[CH:19]=[CH:20][CH:21]=[C:17]1[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2Participants
3
Procedure
The title compound was prepared as described for Example 37 using 5-bromooxindole and tri-n-butyl(2-thienyl)tin: MS (ES) n/z 216 (M++1).
Sources & evidence
- ORD record
- ord-b1dbea2658be4e349d8b8f719350789f
- Source dataset
- uspto-grants-2008_07
- Patent number
- US07399780B2
Reaction notes
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