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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7516Generated: October 23, 2026

Benzaldehyde → HCID 178418783, compound

https://huagongshe.com/en/reaction/7516

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
Reactant2-AminopyridineHCID 10439—
ReactantTert-Butyl isocyanideHCID 23577—
ReactantCyclohexanecarbonyl chlorideHCID 75938—
SolventPerchloric AcidHCID 24247—
ProductHCID 178418783HCID 178418783—

Reaction Steps

Example 10 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyridine (0.1 M, DCM), 0.575 ml (0.115 mmol) tert.-butylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) benzaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process steps b) to d) by reacting the resultant reaction product with 0.4 mmol cyclohexylcarboxylic acid chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087607B2
Source datasetuspto-grants-2006_08
ORD IDord-cb1d1f9e1bc94670a80cb99ed22a0e19
Source noteuspto-grants-2006_08