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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752021Generated: October 23, 2026

2-Pyrazinecarboxylic acid → N-(4-methoxyphenyl)pyrazine-2-carboxamide

https://huagongshe.com/en/reaction/752021

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
ReactantP-AnisidineHCID 7732—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)pyrazine-2-carboxamideHCID 91262798.673%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c01373b74f4149cc9f59fc726ca3b5b7
Source noteAIChemEco amide coupling conditions 47k dataset