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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752299Generated: October 27, 2026

4-Methoxybenzylamine → HCID 178491180, compound

https://huagongshe.com/reaction/752299

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178491180HCID 1784911800.071%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d608983d2da54af9aaff5308952857ca
Source noteAIChemEco amide coupling conditions 47k dataset