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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7528Generated: October 26, 2026

2-Aminothiazole → HCID 178418835, compound

https://huagongshe.com/reaction/7528

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminothiazoleHCID 2155—
ReactantAcetyl chlorideHCID 6367—
Reactant2-PyridinecarboxaldehydeHCID 14273—
ReactantCyclohexyl isocyanideHCID 79129—
SolventPerchloric AcidHCID 24247—
ProductHCID 178418835HCID 178418835—

Reaction Steps

Example 22 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-aminothiazole (0.1 M, DCM), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) pyridine-2-carbaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087607B2
Source datasetuspto-grants-2006_08
ORD IDord-ae6a67ef2da04b86bbc2bf27489624ee
Source noteuspto-grants-2006_08