Phenyl Isothiocyanate → 4,4'-Di(phenylthiocarbamoylamino)benzanilide

Participants

Role	Name	HCID	Charge
Reactant	Phenyl Isothiocyanate	HCID 7673	—
Reactant	4,4'-Diaminobenzanilide	HCID 69917	—
Solvent	Acetone	HCID 180	—
Product	4,4'-Di(phenylthiocarbamoylamino)benzanilide	HCID 19693281	72.3%

Reaction Conditions

Temperature	55 °C

Reaction Steps

4,4'-Diaminobenzanilide (0.658 g, 2.5 mM) was dissolved in 20 ml of acetone, and 2 equivalents of phenylisothiocyanate (0.676 g, 5 mM) was added. The mixture was stirred at 55° C. for 10 minutes. After cooling, the reaction mixture was filtered, and washed with acetone/n-hexane to obtain 0.90 g (72.3% yield) of a colorless crystal of compound A-15.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05723075
Source dataset	uspto-grants-1998_03
ORD ID	ord-e8642ae0ecb248809067cd131fde0eed
Source note	uspto-grants-1998_03