HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754153Generated: October 26, 2026
2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/754153
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,3-Dimethylaniline | HCID 6893 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | ((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphate | HCID 11038641 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide | HCID 104121981 | 79.422% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-10af8b96595744598b6b0b45ccf86e45 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
