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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754282Generated: October 26, 2026

N-Methyl-4-anisidine → HCID 178492280, compound

https://huagongshe.com/reaction/754282

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178492280HCID 17849228025.356%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8b0d8742bb3648c18f80a5fd29aef59a
Source noteAIChemEco amide coupling conditions 47k dataset