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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7550Generated: October 26, 2026

Cyclopentanecarbonyl chloride → N-{1-[3-(4-methyl-1-naphthyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}cyclopentanecarboxamide

https://huagongshe.com/reaction/7550

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentanecarbonyl chlorideHCID 78284—
Reactant6-(1-aminopropyl)-3-(4-methyl-1-naphthyl)-1,2,4-triazin-5(4H)-oneHCID 135752639—
ProductN-{1-[3-(4-methyl-1-naphthyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}cyclopentanecarboxamideHCID 135752584—

Reaction Steps

In analogy to the procedure for Example 36A, 600 mg (2.04 mmol) 6-(1-aminopropyl)-3-(4-methyl-1-naphthyl)-1,2,4-triazin-5(4H)-one, 270 mg (2.04 mmol) cyclopentanecarbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087605B2
Source datasetuspto-grants-2006_08
ORD IDord-3515f6f04b2e4e65bb53076e6c2d4d2c
Source noteuspto-grants-2006_08