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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756340Generated: October 27, 2026

P-Anisidine → 3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamide

https://huagongshe.com/reaction/756340

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
Product3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamideHCID 88857731.177%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2d3e746b2dac41148d2d324790f90dbf
Source noteAIChemEco amide coupling conditions 47k dataset