Benzyl Isothiocyanate → 1,5-Di(benzylthiocarbamoylamino)naphthalene

Participants

Role	Name	HCID	Charge
Reactant	Benzyl Isothiocyanate	HCID 2346	—
Reactant	1,5-Diaminonaphthalene	HCID 16720	—
Solvent	Ethyl Acetate	HCID 8857	—
Product	1,5-Di(benzylthiocarbamoylamino)naphthalene	HCID 19693280	30.7%

Reaction Conditions

Temperature	80 °C

Reaction Steps

1,5-Naphthalenediamine (0.791 g, 5 mM) was dissolved in 20 ml of ethyl acetate, and 2 equivalents of benzylisothiocyanate (1.492 g, 10 mM) were added. The mixture was stirred at 80° C. for 30 minutes. After cooling, the reaction mixture was filtered, and washed with ethylacetate/n-hexane to obtain 0.70 g (30.7% yield) of a colorless crystal of compound A-29.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05723075
Source dataset	uspto-grants-1998_03
ORD ID	ord-d421bcbbd72f4cb18c2bcf8464545117
Source note	uspto-grants-1998_03