1-((Tert-butoxy)carbonyl)pyrrolidine-3-carboxylic acid → HCID 178441299, compound

HRID 76285

Reaction equation

HRID 76285 reaction equation
[C:1]([N:5]1[CH:9]=[C:8]([CH2:10][CH2:11][CH2:12][CH3:13])[C:7](=[NH:14])[S:6]1)([CH3:4])([CH3:3])[CH3:2].[C:15]([O:19][C:20]([N:22]1[CH2:26][CH2:25][CH:24]([C:27](O)=[O:28])[CH2:23]1)=[O:21])([CH3:18])([CH3:17])[CH3:16]>>[CH2:10]([C:8]1=[CH:9][N:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[S:6]/[C:7]/1=[N:14]\[C:27]([CH:24]1[CH2:25][CH2:26][N:22]([C:20]([O:19][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:21])[CH2:23]1)=[O:28])[CH2:11][CH2:12][CH3:13]

Participants

3

Reactant 2

HCID 27605291-((Tert-butoxy)carbonyl)pyrrolidine-3-carboxylic acidHCID 668672282-tert-Butyl-4-butylisothiazol-5(2H)-imine

Product 1

HCID 178441299HCID 178441299, compound

Procedure

The product from Example 92B and 1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid (Aldrich) were processed using the method described in Example 92C to afford the title compound. MS (ESI+) m/z 410 (M+H)+.

Sources & evidence

ORD record
ord-68cd0f95b25944bb9ea8c16c60a21371
Source dataset
uspto-grants-2014_09
Patent number
US08835475B2

Linked notes

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