Trimethylamine oxide → 7-Oxoheptanenitrile

Reaction equation

Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]#[N:9].C[N+]([O-:14])(C)C>>[O:14]=[CH:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]#[N:9]

Participants

Reactant 2

HCID 1145Trimethylamine oxide

HCID 88737Heptanenitrile, 7-bromo-

Product 1

HCID 113440197-Oxoheptanenitrile

Procedure

7-bromoheptanenitrile and trimethylamine oxide were processed using the method described in Example 137A to afford the title compound. MS (ESI+) m/z 143 (M+NH4)+.

Sources & evidence

ORD record: ord-ed5cb844ea7d457180a5c6509aef0429
Source dataset: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08835475B2

Reaction notes

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