Furan, 2-(bromomethyl)tetrahydro- → 5-propyl-3-((tetrahydrofuran-2-yl)methyl)thiazol-2(3H)-imine

HRID 78485

Reaction equation

HRID 78485 reaction equation
[CH2:1]([C:4]1[S:8][C:7]([NH2:9])=[N:6][CH:5]=1)[CH2:2][CH3:3].Br[CH2:11][CH:12]1[CH2:16][CH2:15][CH2:14][O:13]1>>[CH2:1]([C:4]1[S:8][C:7](=[NH:9])[N:6]([CH2:11][CH:12]2[CH2:16][CH2:15][CH2:14][O:13]2)[CH:5]=1)[CH2:2][CH3:3]

Participants

3

Reactant 2

HCID 14501Furan, 2-(bromomethyl)tetrahydro-HCID 32822365-Propyl-1,3-thiazol-2-amine

Product 1

HCID 686240445-propyl-3-((tetrahydrofuran-2-yl)methyl)thiazol-2(3H)-imine

Procedure

A mixture of 5-propylthiazol-2-amine and 2-(bromomethyl)tetrahydrofuran were processed using the method described in Example 2A to afford the title compound. MS (ESI) m/z 227 (M+H)+.

Sources & evidence

ORD record
ord-7508b042c19d49a6a9808d0727fbf4f8
Source dataset
uspto-grants-2014_09
Patent number
US08841334B2

Linked notes

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