Phosgen toluene → HCID 86709886, compound

HRID 78707

Reaction equation

HRID 78707 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][O:11][C:12]1[CH:18]=[CH:17][C:15]([NH2:16])=[CH:14][CH:13]=1.[C:19](Cl)(Cl)=[O:20].C1(C)C=CC=CC=1>C(Cl)Cl>[N:16]([C:15]1[CH:14]=[CH:13][C:12]([O:11][CH2:10][CH2:9][O:8][CH2:7][CH2:6][O:5][CH2:4][CH2:3][O:2][CH3:1])=[CH:18][CH:17]=1)=[C:19]=[O:20]

Participants

4

Reactant 2

HCID 19083224Phosgen tolueneHCID 219176404-(2-(2-(2-Methoxyethoxy)ethoxy)ethoxy)aniline

Product 1

HCID 86709886HCID 86709886, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a stirred 0° C. solution of 18 (0.59 g, 2.29 mmol) in DCM (23 mL) was added a 20% phosgene/toluene solution (2.42 mL). After stirring for 3 h the reaction mixture was concentrated under reduced pressure and carried on without further purification.

Workup

  1. concentrationwas concentrated under reduced pressure
  2. customcarried on without further purification

Sources & evidence

ORD record
ord-4d9ae502f1a9421a908e220b967daec3
Source dataset
uspto-grants-2014_09
Patent number
US08841460B2

Linked notes

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