HuagongsheHuagongshe Chemistry Print Report · For research reference only
9-Cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-amine → N-(5-((3S)-3-((tert-butyl(dimethyl)silyl)oxy)-1-pyrrolidinyl)-2-pyridinyl)-9-cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9-Cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-amine | HCID 58299688 | — |
| Reactant | (S)-5-(3-(tert-butyldimethylsilyloxy)-pyrrolidin-1-yl)-2-chloropyridine | HCID 58299793 | — |
| Product | N-(5-((3S)-3-((tert-butyl(dimethyl)silyl)oxy)-1-pyrrolidinyl)-2-pyridinyl)-9-cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-amine | HCID 58299567 | — |
Reaction Steps
Compound 280 was prepared from compound 245 and (S)-5-(3-(tert-butyldimethylsilyloxy)-pyrrolidin-1-yl)-2-chloropyridine using methods described in Example 186a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08841312B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-6b547d2afd0349fabf80dffe314f0878 |
| Source note | uspto-grants-2014_09 |