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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7964Generated: October 25, 2026

6-(3,4-difluorophenyl)-4-hydroxymethyl-2-isobutyl-2H-pyridazin-3-one → 6-(3,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one

https://huagongshe.com/reaction/7964

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(3,4-difluorophenyl)-4-hydroxymethyl-2-isobutyl-2H-pyridazin-3-oneHCID 21991453—
Reactant6-(3-fluoro-4-methylphenyl)-2-isobutyl-4-methane-sulfonyloxymethyl-2H-pyridazin-3-oneHCID 21991531—
Product6-(3,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-oneHCID 2199152081.4%

Reaction Steps

Following the procedure of Example 1 (9), 6-(3,4-difluorophenyl)-4-hydroxymethyl-2-isobutyl-2H-pyridazin-3-one was reacted to yield the title compound as colorless fine-needles (yield: 81.4%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-44a0c0f88285404fb3b5edd818d8b15f
Source noteuspto-grants-2006_08