Dichloromethane → 1-(Chloromethyl)-4-fluoro-2-methylbenzene

Reaction equation

[Cl:15][CH2:16][Cl:17].[F:1][c:2]1[cH:3][c:4]([CH3:10])[c:5]([CH2:8][OH:9])[cH:6][cH:7]1.[S:11]([Cl:12])([Cl:13])=[O:14]>>[F:1][c:2]1[cH:3][c:4]([CH3:10])[c:5]([CH2:8][Cl:13])[cH:6][cH:7]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 24386Thionyl Chloride

HCID 3872017(4-Fluoro-2-methylphenyl)methanol

Product 1

HCID 205118161-(Chloromethyl)-4-fluoro-2-methylbenzene

Sources & evidence

ORD record: ord-e146b63cfe724fec8e5f37d8ee1639c3
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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