2-cyclopropyl-1H-imidazole → [5-(2-Cyclopropyl-imidazol-1-yl)-2-morpholin-4-yl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone

HRID 801070

Reaction equation

HRID 801070 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N:26]2[CH2:27][CH2:28][O:29][CH2:30][CH2:31]2)[c:6]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]3)[CH2:14][CH2:15]2)[cH:7]1.[CH:32]1([c:35]2[nH:36][cH:37][cH:38][n:39]2)[CH2:33][CH2:34]1>>[c:2]1(-[n:36]2[c:35]([CH:32]3[CH2:33][CH2:34]3)[n:39][cH:38][cH:37]2)[cH:3][cH:4][c:5]([N:26]2[CH2:27][CH2:28][O:29][CH2:30][CH2:31]2)[c:6]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]3)[CH2:14][CH2:15]2)[cH:7]1

Participants

3

Reactant 2

HCID 179423832-cyclopropyl-1H-imidazoleHCID 59793730(5-Bromo-2-morpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone

Product 1

HCID 68841917[5-(2-Cyclopropyl-imidazol-1-yl)-2-morpholin-4-yl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone

Sources & evidence

ORD record
ord-8e58056d76e540998d6232a5595ce2ac
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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