Acetonitrile → Methyl 3-(2,5-dimethyl-1H-pyrrol-1-yl)-6-hydroxy-5-(trifluoromethyl)picolinate

Reaction equation

[CH3:1][c:2]1[n:3](-[c:8]2[c:9]([C:20](=[O:21])[O:22][CH3:23])[n:10][c:11]([O:18][CH3:19])[c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[c:4]([CH3:7])[cH:5][cH:6]1.[CH3:29][C:30]#[N:31].[Si:24]([Cl:25])([CH3:26])([CH3:27])[CH3:28]>>[CH3:1][c:2]1[n:3](-[c:8]2[c:9]([C:20](=[O:21])[O:22][CH3:23])[n:10][c:11]([OH:18])[c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[c:4]([CH3:7])[cH:5][cH:6]1

Participants

Reactant 3

HCID 6342Acetonitrile

HCID 6397Chlorotrimethylsilane

HCID 67387130HCID 67387130, compound

Product 1

HCID 178499131Methyl 3-(2,5-dimethyl-1H-pyrrol-1-yl)-6-hydroxy-5-(trifluoromethyl)picolinate

Sources & evidence

ORD record: ord-d1ea41c8f03141968f0a8fe7aae4a712
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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