8-Chloro-1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → 8-Chloro-1-cyclopropyl-7-[3-[(cyclopropylamino)methyl]-4-fluoropyrrolidin-1-yl]-6-fluoro-4-oxoquinoline-3-carboxylic acid
Reaction equation
[CH:21]1([NH:24][CH2:25][CH:26]2[CH2:27][NH:28][CH2:29][CH:30]2[F:31])[CH2:22][CH2:23]1.[Cl:1][c:2]1[c:3]([F:20])[c:4]([F:19])[cH:5][c:6]2[c:7](=[O:18])[c:8]([C:15](=[O:16])[OH:17])[cH:9][n:10]([CH:12]3[CH2:13][CH2:14]3)[c:11]12>>[Cl:1][c:2]1[c:3]([N:28]2[CH2:27][CH:26]([CH2:25][NH:24][CH:21]3[CH2:22][CH2:23]3)[CH:30]([F:31])[CH2:29]2)[c:4]([F:19])[cH:5][c:6]2[c:7](=[O:18])[c:8]([C:15](=[O:16])[OH:17])[cH:9][n:10]([CH:12]3[CH2:13][CH2:14]3)[c:11]12Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f3c3e6a17d4b4fd089e7abdec29e5a57
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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