4,6-Dichloro-3-methylpyridazine → 3-[1-(5-Chloro-6-methylpyridazin-3-yl)piperidin-3-yl]-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one

HRID 801540

Reaction equation

HRID 801540 reaction equation
[Cl:25][c:26]1[c:27]([CH3:33])[n:28][n:29][c:30]([Cl:32])[cH:31]1.[OH:1][C:2]([CH2:3][C:4]1([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[CH2:5][CH2:6][N:7]([CH:11]2[CH2:12][NH:13][CH2:14][CH2:15][CH2:16]2)[C:8](=[O:10])[O:9]1)([CH3:23])[CH3:24]>>[OH:1][C:2]([CH2:3][C:4]1([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[CH2:5][CH2:6][N:7]([CH:11]2[CH2:12][N:13]([c:30]3[n:29][n:28][c:27]([CH3:33])[c:26]([Cl:25])[cH:31]3)[CH2:14][CH2:15][CH2:16]2)[C:8](=[O:10])[O:9]1)([CH3:23])[CH3:24]

Participants

3

Reactant 2

HCID 587170494,6-Dichloro-3-methylpyridazineHCID 667466566-(2-Hydroxy-2-methylpropyl)-6-phenyl-3-piperidin-3-yl-1,3-oxazinan-2-one

Product 1

HCID 670198443-[1-(5-Chloro-6-methylpyridazin-3-yl)piperidin-3-yl]-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one

Sources & evidence

ORD record
ord-b054c791a0024b28a45a60de05f1ec0d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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