Methanol → 4-Hydroxy-3-methyl-4-trifluoromethyl-piperidine
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH3:19])[C:11]([C:14]([F:15])([F:16])[F:17])([OH:18])[CH2:12][CH2:13]1.[CH3:20][OH:21].[H:22][H:23].[OH-:24].[OH-:26].[Pd+2:25]>>[NH:8]1[CH2:9][CH:10]([CH3:19])[C:11]([C:14]([F:15])([F:16])[F:17])([OH:18])[CH2:12][CH2:13]1Participants
6
Sources & evidence
- ORD record
- ord-1268cfef294f48cf83b007f51324b7a4
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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